Sildigra Xl Plus 150mg Tablet

Description

What is Sildigra XL Plus 150mg?

Sildigra XL Plus 150mg is an anti-ed medicine designed for the treatment of erectile dysfunction (ED) in adult men. It contains sildenafil citrate, a potent inhibitor of phosphodiesterase type 5 (PDE5). By blocking PDE5, sildenafil boosts the vasodilatory effects of nitric oxide. This means that more blood flows to the corpus cavernosum of the penis when you are sexually aroused. This mechanism facilitates the achievement and maintenance of penile erection sufficient for satisfactory sexual activity.

The dosage strength of 150mg denotes a higher potency compared to conventional sildenafil formulations. Sildigra XL Plus 150mg is administered orally and is typically prescribed on an as-needed basis prior to sexual activity. However, it is crucial to strictly follow the dosage regimen that a licensed healthcare professional has prescribed because misuse or overuse may result in negative side effects or complications.

What are The Uses of Sildigra XL Plus 150mg?

• The drug Sildigra XL Plus 150mg, which includes sildenafil citrate, helps adult men with ED. Elerectile dysfunction is the inability to get or keep an erection for sexual behavior. Millions of men around the world have this problem.
• A selective inhibitor of cGMP-specific PDE5, sildenafil citrate, raises the response to sexual arousal. During sexual excitement, nerve endings and endothelial cells in the penis corpus cavernosum produce nitric oxide. Stimulating guanylate cyclase to make more cyclic guanosine monophosphate (cGMP) relaxes smooth muscle cells and makes penile vessels bigger. Vasodilation raises blood flow to penile tissue, which creates an erection and a full penis.
• Sidigra XL Plus 150 mg taken by mouth stops PDE5 from breaking down cGMP, which increases the effects of nitric oxide on blood vessels and the penile erection. Higher blood flow to the corpus cavernosum improves penile function and lets the patient stay stiff for good sexual performance.
• That’s not what Sildigra XL Plus 150mg is supposed to do; it’s supposed to help with sexual arousal. The effectiveness of sildenafil citrate may change depending on the person’s reaction and tolerance.
• Even though sildenafil citrate is mostly used to treat erectile dysfunction (ED), its ability to widen blood vessels has also shown promise in treating pulmonary arterial hypertension (PAH). Simdigra XL Plus 150 mg is meant to help erectile dysfunction, so a different dose and strength will be needed for PAH.
• Lastly, Sildigra XL Plus 150mg treats erectile dysfunction by focusing on the pathophysiology of the problem and returning normal erectile function. This makes people happier with their sexual health and overall quality of life.

What are The Dosage Guidelines for Sildigra XL Plus 150mg Tablets?

The recommended dosage of Sildigra XL Plus 150mg is typically one tablet taken orally with water, approximately 30–60 minutes before sexual activity.  Avoid consuming alcohol or large meals high in fat before taking Sildigra XL Plus, as this may affect its effectiveness.  Do not exceed the prescribed dosage to avoid potential side effects or complications.

Missed Dosage Guidelines:

Take your Sildigra XL Plus 150mg as soon as you remember if you forget to. But if it’s almost time for your next dose, don’t take the one you missed. Instead, go back to your normal dosing schedule. Do not take two of the same medicine to make up for one you forgot. Talk to your healthcare provider if you are worried or have questions about missing doses.

Overdosage Guidelines:

Sidigra XL Plus 150 mg overdose? Immediately get medical help or call a poison control center. For example, severe dizziness, passing out, or a long-lasting erection are all signs of abuse. Exceeding the recommended dose is very important to avoid bad effects and problems.

How does Sildigra XL Plus 150mg Tablet Work?

Sildigra XL Plus 150mg pills contain sildenafil citrate, which is a strong PDE5 inhibitor. In the corpus cavernosum of the penis, sildenafil changes the cyclic guanosine monophosphate (cGMP) pathway. This changes the tone of smooth muscles and the way blood vessels work.

Nerve endings and vascular cells release NO when they are sexually stimulated. This turns on guanylate cyclase. The enzyme guanylate cyclase changes GTP into cGMP, which raises the amount of cGMP inside cells. The cGMP molecule acts as a second messenger and sets off biochemical reactions that relax smooth muscle and widen penile arteries.

Because CGMP widens blood vessels, blood can flow into the corpus cavernosum, filling up the penis and causing an erection. Phosphodiesterase type 5 (PDE5), which breaks down cGMP and prevents its vasodilation, tightly controls the erectile reaction.

The sildenafil citrate in Sildigra XL Plus 150mg pills blocks PDE5 in a specific way, which increases cGMP levels in the corpus cavernosum. Sildenafil blocks PDE5 to improve blood flow to the penis and relax smooth muscles. For sexual actions, this erectile response enhancer helps get and keep an erection.

It is very important to know that sildenafil citrate does not help men get erections when they are not sexually aroused. The start and length of the effect may be different depending on the dose, metabolic variability, and other drugs that are taken at the same time.

To sum up, Sildigra XL Plus 150mg pills treat erectile dysfunction by focusing on its underlying causes and restoring erectile function, which enhances sexual energy and pleasure.

What are The Side Effects of Sildigra XL Plus 150mg Tablets?

• Sildigra XL Plus 150mg tablets contain sildenafil citrate, which can cause side effects that range from mild to serious and affect different body systems.
• Among the cardiovascular effects are changes in blood pressure that can cause hypotension or hypertension, as well as flushing, tremors, or fainting.
• GI problems like dyspepsia, nausea, or diarrhoea are common but generally only last for a short time.
• Neurological effects like headaches or dizziness may happen, but they usually go away after a while of use.
• Visual problems, like blurred vision or changes in colour vision, need to be taken seriously.
• In some rare cases, a doctor needs to treat sudden vision loss right away.
• Rarely do people describe hearing problems like sudden loss of hearing or ringing in the ears. Priapism, which is an erection that lasts for a long time and hurts, needs medical help right away.
• An allergic reaction can show up as a rash, swelling, or trouble breathing. Anaphylaxis is very rare but very bad.
• In very few cases, musculoskeletal pain, kidney damage, and liver damage have been recorded.
• Other bad effects include stuffy noses, nosebleeds, and illnesses in the urinary or respiratory tracts.

Precautions & Warnings:

There are some things you should know before taking Sildigra XL Plus 150mg pills.

• Patients who already have heart problems like heart disease or high blood pressure should be extra careful when taking sildenafil citrate because it might increase the risk of heart problems. Interactions between drugs, especially those involving nitrates or nitric oxide donors, can cause severe low blood pressure, so patients must tell their doctors about all of their medicines.
• As a rare but dangerous side effect, priapism needs to be treated right away to avoid further problems.
• Vision and hearing changes, hypersensitivity responses, and drinking alcohol should all be closely watched for bad effects.
• Patients with serious kidney or liver damage may need to change their doses or be closely watched because their bodies may not be able to get rid of drugs as quickly.
• It is not recommended that children use Sildigra XL Plus 150mg pills, and it is also not known if sildenafil citrate is safe for women who are pregnant or breastfeeding.

When Not to Take Sildigra XL Plus 150mg Tablet ?

Sildigra XL Plus 150mg tablets should not be taken in certain circumstances:

• Given the risk of significant hypotension, nitrates and nitric oxide donors should not be used.
• Do not take it if you have Child-Pugh class C liver damage.
• Do not use if renal impairment is severe (creatinine clearance <30 mL/min).
• Not for people who have had a myocardial attack, stroke, or life-threatening arrhythmia.
• Not for those with retinitis pigmentosa or other inherited degenerative eye conditions
• Avoid sildenafil if you are allergic to it.
• Do not use guanylate cyclase stimulators to avoid low blood pressure.
• Avoid if you’re pregnant or under 18.
• Avoid if you have bleeding issues or peptic ulcer illness.
• Due to interactions, avoid grapefruit juice.

Interaction:

Sildigra XL Plus 150 mg drug interactions:

• There is a high chance of severe hypotension and cardiovascular collapse with nitrates and nitric oxide donors.
• Increased hypotensive effects can cause orthostatic hypotension or dizziness; users need to change their doses.
• Increased hypotensive effects; dosage changes and blood pressure tracking are needed.
• Stop the metabolism of sildenafil, which raises plasma levels and increases the chance of side effects.
• CYP3A4 Inhibitors raised sildenafil levels may make effects last longer and raise the risk of adverse responses.
• Guanylate Cyclase Stimulators are not recommended because they highly increase the chance of severe low blood pressure.
• Inhibiting sildenafil metabolism, grapefruit juice raises plasma levels and the risk of side effects.
• Alcohol raises the risk of dizziness or fainting and makes sildenafil-induced low blood pressure worse.
• The effects of phosphodiesterase inhibitors are stronger and the chance of adverse reactions is higher.
• Alpha-adrenergic antagonists bind to and raise blood pressure, raising the risk of hypotension.

FAQs:

1) What is the Sildigra XL Plus 150mg tablet used for?

Ans: Sildigra XL Plus 150mg tablet is primarily used to treat erectile dysfunction (ED) in men, facilitating the attainment and maintenance of penile erection during sexual activity.

2) How does Sildigra XL Plus 150mg tablet work?

Ans: Sildigra XL Plus 150mg tablet contains sildenafil citrate, which works by increasing blood flow to the penis during sexual stimulation, thereby aiding in the achievement and sustenance of an erection.

3) How long does Sildigra XL Plus 150mg tablet last?

Ans: The effects of Sildigra XL Plus 150mg tablet can last up to 4-6 hours after administration, during which time sexual stimulation can lead to the desired erection.

4) Can I take Sildigra XL Plus 150mg tablet with food?

Ans: Sildigra tablets can be taken with or without food. However, consuming a heavy or high-fat meal before taking the medication may delay its onset of action.

5) Are there any medications that interact with Sildigra XL Plus 150mg tablet?

Ans: Yes, Sildigra XL Plus 150mg tablet may interact with certain medications, particularly nitrates, alpha-blockers, and drugs that inhibit the cytochrome P450 3A4 enzyme system

6) Can I take Sildigra XL Plus 150mg tablet if I have heart problems?

Ans: Patients with underlying cardiovascular conditions should use Sildigra XL Plus 150mg tablet with caution and under the guidance of a healthcare professional, as it may pose a risk of exacerbating cardiac symptoms